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Keratitis, Ichthyosis, and Deafness (KID) Syndrome in Half Sibs
Author(s) -
KonéPaut Isabelle,
Hesse Sylvie,
Palix Christian,
Rey Réjane,
Rémédiani Karine,
Garnier JeanMarc,
Berbis Philippe
Publication year - 1998
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1998.tb01320.x
Subject(s) - ichthyosis , keratitis , medicine , congenital ichthyosis , dermatology , hearing loss , congenital disorder , cornea , consanguinity , pediatrics , ophthalmology , audiology , surgery
The keratitis, ichthyosis, and deafness (KID) syndrome is a rare congenital disorder of the ectoderm characterized by diffuse hyperkeratotic erythroderma, keratitis with neovascularization of the cornea, and severe neurosensory hearing loss. A familial occurrence of this syndrome has been mentioned in four reports including three of vertical transmission and one of two affected sisters born from consanguineous, unaffected parents. We report for the first time a familial case of KID syndrome in two half siblings born to the same unaffected mother. This new observation allows us to propose various hypotheses about its mode of inheritance.