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An Intriguing Case of LEOPARD Syndrome
Author(s) -
Schepis Carmelo,
Greco Donatella,
Siragusa Maddalena,
Batolo Dario,
Romano Corrado
Publication year - 1998
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1998.tb01297.x
Subject(s) - leopard , medicine , dermatology , neurofibroma , ichthyosis , neurofibromatosis , café au lait spot , hyperkeratosis , pathology , zoology , biology
We report a 9‐year‐old boy affected by LEOPARD syndrome, who also had ichthyosis, axillary freckling, two caf#eA au lait spots, and one neurofibroma. The diagnosis of LEOPARD syndrome has been made on clinical grounds, whereas the ichthyosis and neurofibroma have been histologically confirmed. The analogies between LEOPARD syndrome and neurofibromatosis have been discussed. Finally, we maintain this case is an example of the multiple lentigines syndrome/LEOPARD syndrome spectrum.