Premium
Lymphedema as a Postulated Cause of Cutis Verticis Gyrata in Turner Syndrome
Author(s) -
Larralde Margarita,
Gardner Stephanie S.,
Torrado Maria del V.,
Fernhoff Paul M.,
Muñoz Andrea E. Santos,
Spraker Mary K.,
Sybert Virginia P.
Publication year - 1998
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1998.tb01262.x
Subject(s) - medicine , lymphedema , in utero , dermatology , nail (fastener) , turner syndrome , pregnancy , fetus , materials science , cancer , biology , breast cancer , metallurgy , genetics
Abstract: Unusual skin lesions were present at birth in four infants with Turner syndrome. The skin changes in these patients appear to have resulted either from in utero entrapment or pinching of edematous skin or from redundant skin remaining after in utero resolution of lymphedema. Distention by lymphedema is thought to cause several of the phenotypic characteristics seen in patients with Turner syndrome, including nuchal webbing and nail changes. In three of these patients the clinical appearance of the skin changes was similar to cutis verticis gyrata, marked by fixed thickened plaques in folds.