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A Case of Hypopigmented Mycosis Fungoides in a Young Caucasian Boy
Author(s) -
Landro Anna Di,
Marchesi Lorenzo,
Naldi Luigi,
Motta Teresio,
Cainelli Tullio
Publication year - 1997
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1997.tb00687.x
Subject(s) - mycosis fungoides , dermatology , medicine , hypopigmentation , natural history , peripheral t cell lymphoma , puva therapy , differential diagnosis , disease , pathology , lymphoma , immunology , t cell , immune system , psoriasis
Hypopigmented mycosis fungoides is a variant of mycosis fungoides characterized by the presence of hypopigmented patches as the sole manifestation of the disease. It has been described aimost always in young black or dark‐skinned patients. The only white patient described was a 64‐year‐oid woman who not oniy had hypopigmented lesions, but also nodular lesions with lymphadenopathy. We describe hypopigmented lesions arising in a white boy 12 years of age, born in northern Italy, without any foreign ancestors. The microscopic alterations, with epidermotropism, the immunoiogic markers, the negativity of T‐cell receptor gene rearrangement, and the good response to PUVA therapy correspond to the main findings in black patients with this disease. Long‐term follow‐up of these patients is important to obtain better knowledge of the natural history of the disorder, Hypopigmented mycosis fungoides must now be included in the differential diagnosis of hypopigmented macular lesions not only in black or dark‐skinned patients but also in white patients.