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Disseminated Fusariosis
Author(s) -
Repiso T.,
GarcíaPatos V.,
Martin N.,
Creus M.,
Bastida P.,
Castells A.
Publication year - 1996
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1996.tb01416.x
Subject(s) - medicine , fungemia , pathology , mycosis , dermatology , fusariosis , surgery , horticulture , fusarium , biology
A 7‐year‐old boy with T cell acute lymphoblastic leukemia developed disseminated hyalohyphomycosis due to Fusarium solani. The clinical features included fever, severe myalgia, documented fungemia with F. solani , an ecthyma gangrenosum‐like lesion next to a peripheral venous catheter, and disseminated pustules. Severe neutropenia due to chemotherapy was the most revelant risk factor. Histopathologic study of the ecthyma gangrenosum‐like lesion, as well as pustular lesions, revealed epidermal necrosis and an inflammatory infiltrate in the upper dermis, with numerous septate hyphae demonstrated by periodic acid‐Schiff stain. Clinical resolution was achieved with granulocyte colony‐stimulating factor and amphotericin B administration. Our case suggests that the peripheral venous access was probably the portal of entry of the fungus.