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Ki‐1 Large Cell Lymphoma with Regressing Lesions in a Child
Author(s) -
Bittencourt Achiléa Lisboa,
Mendonça Nubia,
De Freitas Luiz Antonio Rodrigues,
Schnitzer Bertram
Publication year - 1992
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1992.tb01226.x
Subject(s) - medicine , lymphoma , pathology , anaplastic large cell lymphoma , differential diagnosis , large cell , large cell lymphoma , disease , cancer , adenocarcinoma
An 8‐year‐old boy was seen with a cutaneous Ki‐1 anaplastic, large cell lymphoma with multiple lesions. Some of the lesions showed spontaneous regression. During more than seven years of disease no systemic Involvement was observed, but recurrent, self‐healing lesions did appear. Histopathologic examination of five lesions revealed a variety of findings, from an inflammatory infiltrate to a highly anaplastic pattern. The neoplastic cells expressed Ki‐1 and leukocyte common antigens. Ultrastructurally, those cells showed ruffled indentations. The differential diagnosis includes microvillous malignant lymphoma. The patient has had a four‐year follow‐up without relapses.