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Cutaneous Lesions in Severe Combined Immunodeficiency: Two Case Reports and a Review of the Literature
Author(s) -
Llorente C. Postigo,
Amorós J. Ivars,
Frutos F. J. Ortiz,
Regueiro J. R.,
Martin R. Llamas,
Tapia A. Guerra,
Diez L. Iglesias
Publication year - 1991
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1991.tb00941.x
Subject(s) - medicine , immunodeficiency , bone marrow transplantation , severe combined immunodeficiency , feature (linguistics) , dermatology , histology , pathology , bone marrow , skin lesion , immunology , immune system , biochemistry , chemistry , linguistics , philosophy , gene
Two patients with severe combined immunodeficiency (SCID) in whom cutaneous lesions were the first clinical feature were studied. Neither the morphology nor the histology of the lesions was uniform, although we have noted some common findings that can, in subsequent cases, lead us to suspect SCID. The immunologic defects were not uniform, representing the two poles of the spectrum of SCID. We believe that early recognition of the skin lesions is very important, since the patient's life expectancy can be increased by a bone marrow transplantation (1).