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Immunologic Investigations in Eight Patients with Incontinentia Pigmenti
Author(s) -
Menni Silvano,
Piccinno Roberta,
Biolchini Angela,
Plebani Anna
Publication year - 1990
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1990.tb01024.x
Subject(s) - incontinentia pigmenti , medicine , immunology , chemotaxis , lymphocyte , antibody , dermatology , pathology , receptor
We studied eight patients with incontinentia pigmenti to investigate the possibility of immunologic abnormalities. In six patients a defect of polymorphonuclear chemotaxis was revealed; lymphocyte subpopulations, serum immunoglobulin levels, and peripheral eosinophiIs were within normal limits. We hope these findings will stimulate further investigations into the mechanisms involved.