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Ataxia‐telangiectasia Associated with Sarcoidosis
Author(s) -
Fleck Robin M.,
Myers Linda K.,
Wasserman Richard L.,
Tigelaar Robert E.,
Freeman Robert G.
Publication year - 1986
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1986.tb00537.x
Subject(s) - medicine , sarcoidosis , ataxia telangiectasia , telangiectasia , dermatology , pathology , systemic disease , arthritis , ataxia , disease , immunology , dna , genetics , dna damage , psychiatry , biology
Ataxia‐telangiectasia and sarcoidosis are diseases characterized by abnormalities of the immune system. We examined a 13‐year‐old female with ataxia‐telangiectasia who developed atrophic, violaceous plaques of the skin and a destructive, polyarticular arthritis. The histologic features of both skin and synovium were most consistent with a diagnosis of sarcoidosis. Interaction of these two immunologic disorders may have resulted in the unusual features of this patient's disease.