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Systemic Glucocorticosteroid Therapy of Skin Disease in Children
Author(s) -
Fritz Karen A.,
Weston William L.
Publication year - 1984
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1111/j.1525-1470.1984.tb01123.x
Subject(s) - medicine , systemic therapy , systemic administration , disease , systemic disease , dermatology , intensive care medicine , cancer , microbiology and biotechnology , breast cancer , in vivo , biology
The role of systemic glucocorticosteroid therapy in the managetnent of dermatologic disorders in children is limited. Most skin diseases requiring the antiinflammatory or antiproliferative effects of steroids are best managed with topical preparations, because they exert local effects almost exclusively and cause few if any systemic side effects when used properly. There are, however, certain skin diseases, which because of their severity or their intrinsic nature, do not respond adequately to these agents. We propose the indications for pharmacologic doses of systemic glucocorticosteroids in dermatologic disease, the preferred route of administration, the most common as well as the more rare side effects of this therapy. Withdrawal of patients from chronic use of these drugs is also discussed.