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Medications in Patients Treated With Therapeutic Plasma Exchange: Prescription Dosage, Timing, and Drug Overdose
Author(s) -
Ibrahim Rami B.,
Balogun Rasheed A.
Publication year - 2012
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.2011.01030.x
Subject(s) - medicine , therapeutic plasma exchange , drug , intensive care medicine , medical prescription , extracorporeal , drug overdose , plasma concentration , therapeutic drug monitoring , pharmacology , emergency medicine , poison control
Therapeutic plasma exchange (TPE) is an extracorporeal process commonly used in clinical medicine for the treatment of a variety of neurological, renal, hematological, dermatological, and other diseases. Inherent to the procedure, patients’ plasma removal may lead to the extraction of drugs they are concurrently receiving. This review discusses the published literature assessing TPE’s influence on different drug classes’ disposition and, when applicable, sets forth management recommendations in cases where the drugs are used at the usual doses and in cases of drug overdose.