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Implications of the Frequent Hemodialysis Network‐Daily Trial
Author(s) -
Raphael Kalani L.,
Cheung Alfred K.
Publication year - 2011
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.2011.00994.x
Subject(s) - medicine , hemodialysis , dialysis , home hemodialysis , intensive care medicine , clinical trial , randomized controlled trial , emergency medicine , physical therapy
Despite many years of experience with hemodialysis, the outcomes of maintenance dialysis patients remain poor. The Frequent Hemodialysis Network‐Daily (FHN‐Daily) Trial found that six times per week in‐center short hemodialysis decreased left ventricular mass and improved self‐reported physical functioning over a 1‐year intervention period compared with conventional thrice‐weekly dialysis. Despite the promising results, caution is needed in the projection of these intermediate outcomes to hard clinical endpoints, such as cardiovascular events and death.