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PROGRESS IN UREMIC TOXIN RESEARCH: The Role of EUTox in Uremic Toxin Research
Author(s) -
Vanholder Raymond,
AbouDeif Omar,
Argiles Angel,
Baurmeister Ulrich,
Beige Joachim,
Brouckaert Peter,
Brunet Philippe,
Cohen Gerald,
De Deyn Peter Paul,
Drüeke Tilman B.,
Fliser Danilo,
Glorieux Griet,
HergetRosenthal Stefan,
Hörl Walter H,
Jankowski Joachim,
Jörres Achim,
Massy Ziad A.,
Mischak Harald,
Perna Alessandra F.,
RodriguezPortillo Juan Mariano,
Spasovski Goce,
Stegmayr Bernd G.,
Stenvinkel Peter,
Thornalley Paul J.,
Wanner Christoph,
Wiecek Andrzej
Publication year - 2009
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.2009.00574.x
Subject(s) - uremic toxins , medicine , kidney disease , library science , engineering ethics , engineering , computer science
In this publication, we review the activities of the European Uremic Toxin Work Group (EUTox) in the field of uremic toxin research. Founded in 1999 under the umbrella of the European Society of Artificial Organs (ESAO), and active since 2000, this group focuses essentially on questions related to solute retention and removal during chronic kidney disease, and on the deleterious impact of those solutes on biological/biochemical systems. As of January 1, 2009, the group had met 28 times; it organized the third meeting, "Uremic Toxins in Cardiovascular Disease," which took place in October 2008 in Amiens, France. The current group is composed of 25 members belonging to 23 European research institutions. As of November 1, 2008, in total 69 papers had been published to which at least two different research groups belonging to EUTox have contributed in a collaborative effort. Of these, 40 papers were on original research and eight were specific EUTox reviews or position statements. A website (http://www.eutox.info) summarizes all relevant information concerning the work group. EUTox also developed an interactive uremic toxin database, where concentrations of known toxins are displayed, to be used by researchers in the field. In the future, EUTox intends to continue its focus on bench to bedside research with specific consideration of proteomics, metabonomics, secretomics, and genomics.