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NON‐CORONARY HEART DISEASE IN DIALYSIS PATIENTS: Hypertrophy and Fibrosis in the Cardiomyopathy of Uremia—Beyond Coronary Heart Disease
Author(s) -
Gross MarieLuise,
Ritz Eberhard
Publication year - 2008
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.2008.00454.x
Subject(s) - medicine , cardiology , uremia , sudden cardiac death , disease , pathological , heart failure , cardiomyopathy , dialysis , fibrosis , myocardial fibrosis , pathogenesis , cardiac hypertrophy , hypertrophic cardiomyopathy , muscle hypertrophy , cause of death
Abstract Cardiac disease is the leading cause of death in uremic patients. In contrast to previous opinion, coronary events account for a relatively small proportion of cardiac deaths, the most common causes being sudden death and heart failure. Against this background the current text will discuss noncoronary cardiac pathology, specifically the pathogenesis and the morphological findings caused by (pathological) cardiac hypertrophy, cardiac interstitial fibrosis and microvascular disease.