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Managing the Failing Allograft
Author(s) -
Kendrick Elizabeth A.,
Davis Connie L.
Publication year - 2005
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.2005.00100.x
Subject(s) - medicine , immunosuppression , anemia , intensive care medicine , kidney disease , depression (economics) , disease , metabolic bone disease , immunology , osteoporosis , economics , macroeconomics
Managing the failing allograft juxtaposes immunosuppressive management and routine chronic kidney disease care. The complications of immunosuppression can be more pronounced in those with renal failure (infection, anemia, bone disease). The withdrawal of immunosuppression may be associated with acute allograft rejection, arthralgias, and the development of antidonor antibodies. Likewise depression is prevalent. Improving well‐being and overall survival necessitates proper titration of immunosuppressive medications and control of blood pressure, anemia, lipids, and glucose along with attention to treatment of depression.

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