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Effect of Increasing Dialysate Flow Rate on K o A and Dialyzer Urea Clearance
Author(s) -
Leypoldt John K.
Publication year - 1998
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1111/j.1525-139x.1998.tb00336.x
Subject(s) - medicine , urea , clearance rate , intensive care medicine , urology , biochemistry , chemistry
I've been told that increasing dialysate flow from 500 to 800 mL/min is of minimal benefit unless the blood flow is relatively high (400‐500 mL/min) and even then the effect is small. I've also been told that increasing dialysate flow changes the membrane properties (not just the solute gradient) and adds significantly to Kt/V. Which is it?