Open AccessShould Hypertension Guidelines Be Changed for Hypertensive Patients With the Metabolic Syndrome?
Author(s) -
Segura Julian,
Banegas Jose Ramon,
GarcíaDonaire Jose Antonio,
RodríguezArtalejo Fernando,
Cruz Juan Jose,
Praga Manuel,
Ruilope Luis Miguel
Publication year - 2007
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1524-6175.2007.06522.x
Subject(s) - medicine , microalbuminuria , blood pressure , metabolic syndrome , diabetes mellitus , incidence (geometry) , endocrinology , physics , optics
The authors analyzed the impact of present guidelines for hypertension management on cardiovascular (CV) risk factors in hypertensive patients with and without the metabolic syndrome (MS). Results in 549 nondiabetic hypertensive patients with a mean follow‐up of 3.8±1.2 years on usual recommended care were reviewed. At baseline, 231 (42.1%) patients had MS and, per the definition, showed significantly higher values of traditional CV risk factors than non‐MS patients. At the end of follow‐up, blood pressure levels were similar in both groups; the lipid profile tended to improve in MS patients. Eighteen MS patients (7.8%) and 7 non‐MS patients (2.2%) developed diabetes ( P <.001). Prevalence of microalbuminuria was reduced in both groups, but it remained significantly higher in MS patients. Usual care of hypertensive patients achieved similar blood pressure and low‐density lipoprotein cholesterol goals, both in MS and non‐MS patients. Global CV risk, however, remained higher in MS patients, as suggested by a 3‐fold higher incidence of new‐onset diabetes (absolute increase of 5.6%) and a 2‐fold increase in microalbuminuria.