Open AccessSerum Uric Acid as a Risk Factor for Cardiovascular and Renal Disease: An Old Controversy Revived
Author(s) -
Viazzi Francesca,
Leoncini Giovanna,
Ratto Elena,
Pontremoli Roberto
Publication year - 2006
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1524-6175.2006.04755.x
Subject(s) - medicine , hyperuricemia , dyslipidemia , uric acid , disease , risk factor , endocrinology
Hyperuricemia is commonly associated with traditional risk factors such as abnormalities in glucose metabolism, dyslipidemia, and hypertension. Recent studies have revived the controversy over the role of serum uric acid as an independent prognostic factor for cardiovascular mortality. The authors review clinical and experimental evidence concerning the role of serum uric acid in the development of cardiovascular and renal damage. Results of trials suggesting that serum uric acid variations over time may have a prognostic impact are also discussed.