Premium
The influence of selected demographic factors and wound location on the concentration of vascular endothelial growth factor ( VEGF ‐ A ) in the wound healing process after neurosurgery: Brief report
Author(s) -
Ślusarz Robert,
Gadomska Grażyna,
Biercewicz Monika,
Grzelak Lech,
Szewczyk Maria T.,
Rość Danuta,
Beuth Wojciech
Publication year - 2012
Publication title -
wound repair and regeneration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.847
H-Index - 109
eISSN - 1524-475X
pISSN - 1067-1927
DOI - 10.1111/j.1524-475x.2012.00821.x
Subject(s) - vegf receptors , medicine , vascular endothelial growth factor , neurosurgery , wound healing , surgery , positive correlation , negative correlation , anesthesia
The main aim of the work was to estimate the influence of selected demographic factors and wound location on the concentration of the vascular endothelial growth factor ( VEGF ‐ A ) in patients after neurosurgical operations. The study included 20 adult patients who received a surgical treatment because of degenerative spine changes. Measurements of the concentration of the VEGF ‐ A in the patients' blood serum were taken three times (the first time––before the operation; the second time––during the first 24 hours after surgery; and the third time––between the fifth and the seventh day after the operation). No statistically significant correlation between the concentration of VEGF ‐ A in the patients' blood serum before and after the operation was noted. A statistically significant correlation between the concentration of VEGF ‐ A in the individual measurements was found. It can be concluded that people with a higher concentration of VEGF ‐ A before surgery obtained a higher concentration of VEGF ‐ A in the measurements taken after the operation. There is a statistically significant link between the patient's age and the concentration of VEGF ‐ A during the immediate postoperative period (the older the patient, the higher the level of VEGF ‐ A is observed).