Open AccessGiant Apocrine Hidradenoma of the Breast
Author(s) -
Knoedler Darly,
Susnik Barbara,
Gonyo Mary Beth,
Osipov Vladimir
Publication year - 2007
Publication title -
the breast journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.533
H-Index - 72
eISSN - 1524-4741
pISSN - 1075-122X
DOI - 10.1111/j.1524-4741.2006.00371.x
Subject(s) - apocrine , medicine , hidradenoma , immunohistochemistry , pathology , malignancy , biopsy , progesterone receptor , estrogen receptor , breast cancer , cancer
We report a case of a 26‐year‐old woman with an 8.0‐cm tumor of the left breast. The tumor was clinically and radiologically suspicious for malignancy. The pathologic evaluation of the core biopsy and the subsequent excision specimen revealed a benign sclerosing, cystic, and papillary adnexal tumor with apocrine and clear cell morphology. The immunohistochemical staining for p63 was positive. Estrogen, progesterone, and Her‐2 receptor immunohistochemical stains were negative. The cytogenetic analysis revealed 46, XX t(11:19) (q21;q13.1) balanced translocation. The final diagnosis was apocrine hidradenoma.