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Reversal of Migraine Symptoms by Helicobacter pylori Eradication Therapy in Patients with Hepatitis‐B‐Related Liver Cirrhosis
Author(s) -
Hong Liu,
Zhao Yunping,
Han Ying,
Guo Wei,
Wang Jun,
Li Xiaohua,
Han Yu,
Fan Daiming
Publication year - 2007
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/j.1523-5378.2007.00512.x
Subject(s) - medicine , cirrhosis , helicobacter pylori , migraine , pathogenesis , gastroenterology , hepatitis b , hepatitis b virus , etiology , immunology , virus
Helicobacter pylori infection might be associated with vascular diseases, such as primary Raynaud phenomenon and coronary heart diseases. The possible mechanism might be due to H. pylori antigens causing intermittent vasospasm of arterioles, which also played roles in the development of liver cirrhosis. Migraine, a functional vascular disease, was observed in many patients with cirrhosis in the clinic. This study aimed to assess the effects of H. pylori eradication on migraine symptoms in patients with hepatitis‐B‐virus‐related cirrhosis. The results clearly showed that the intensity, duration, and frequency of attacks of migraine were significantly reduced in all the patients in whom H. pylori has been eradicated. Thus, the study pushed further insight into the mechanisms of migraine pathogenesis.