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Inflammation, Immunity, and Vaccines for Helicobacter Infection
Author(s) -
Permin Henrik,
Andersen Leif P.
Publication year - 2005
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/j.1523-5378.2005.00337.x
Subject(s) - immunity , inflammation , immunology , helicobacter pylori infection , helicobacter , medicine , immune system , virology , helicobacter pylori
Pro‐inflammatory cytokines such as IL‐18, IFN‐γ, and IL‐1β play a significant role in the inflammation induced by Helicobacter . During the recent years of H. pylori research, the main focus has been on development of vaccines for therapeutic or prophylactic use against the infection. Both bacterial components of H. pylori as well as engineered vaccines have been tested as well as different forms of administration including systemic and oral/intranasal pathways.