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Effects of Illicit Drug Use on Adherence to Prescribed Antiretroviral Medication
Author(s) -
Rosen Marc I.,
Rigsby Michael O.,
Dieckhaus Kevin D.,
Cramer Joyce A.
Publication year - 2003
Publication title -
the american journal on addictions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.997
H-Index - 76
eISSN - 1521-0391
pISSN - 1055-0496
DOI - 10.1111/j.1521-0391.2003.tb00488.x
Subject(s) - medicine , drug , illicit drug , abstinence , human immunodeficiency virus (hiv) , clinical trial , medication adherence , antiretroviral drug , substance abuse , pharmacology , intensive care medicine , psychiatry , antiretroviral therapy , viral load , family medicine
This exploratory analysis compared adherence to antiretroviral medication on days that illicit drugs were used and on matched abstinence days in twelve subjects who used MEMS caps during participation in a clinical trial. Adherence on drug use days was lower in seven subjects, higher in one, and the same in four. Three subjects maintained 100% adherence despite illicit substance use on studied days. Thus, in a subset of patients, the actions involved in procuring drugs and the acute effects of using them contribute to non‐adherence on those specific drug use days.