Premium
Acupuncture for the Treatment of Cocaine Dependence in Methadone‐Maintained Patients
Author(s) -
Margolin Arthur,
Avants S. Kelly,
Chang Patrick,
Kosten Thomas R.
Publication year - 1993
Publication title -
the american journal on addictions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.997
H-Index - 76
eISSN - 1521-0391
pISSN - 1055-0496
DOI - 10.1111/j.1521-0391.1993.tb00419.x
Subject(s) - abstinence , placebo , methadone , craving , desipramine , cocaine dependence , anesthesia , medicine , bupropion , pharmacotherapy , depression (economics) , psychiatry , psychology , smoking cessation , addiction , antidepressant , anxiety , alternative medicine , pathology , macroeconomics , economics
Thirty‐two cocaine‐dependent methadone‐maintained patients received an 8‐week course of auricular acupuncture for the treatment of cocaine dependence. Fifty percent completed treatment; 88% of study completers attained abstinence, defined as providing cocaine‐free urine samples for the last 2 weeks of the study, yielding an overall abstinence rate of 44%. Abstainers reported decreased depression, a shift in self‐definition, decreased craving, and increased aversion to cocaine‐related cues. Post‐hoc comparisons to pharmacotherapy with desipramine (DMI), amantadine (AMA), and placebo revealed a higher abstinence rate for acupuncture (44%) than for AMA (15%) or placebo (13%), but not significantly higher than for DMI (26%).