Premium
Ratio‐Images Calculated From Interictal Positron Emission Tomography and Single‐Photon Emission Computed Tomography for Quantification of the Uncoupling of Brain Metabolism and Perfusion in Epilepsy
Author(s) -
Zubal Ig,
R. A. Avery,
Rik Stokking,
Colin Studholme,
María Corsi,
D I N A H,
Seibyl Jp,
Spencer Ss
Publication year - 2000
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/j.1499-1654.2000.001560.x
Subject(s) - ictal , positron emission tomography , emission computed tomography , single photon emission computed tomography , nuclear medicine , perfusion , epilepsy , magnetic resonance imaging , tomography , temporal lobe , functional imaging , positron emission , medicine , radiology , neuroscience , psychology
Image processing techniques were applied to interictal positron emission tomography (PET) and single-photon emission computed tomography (SPECT) brain images to aid in the localization of epileptogenic foci by calculating a functional image that represents the degree of coupling between perfusion and metabolism. Uncoupling of these two functions has been demonstrated to be a characteristic of epileptogenic tissue in temporal lobe epilepsy and has the potential to serve as a diagnostic measure for localization in other areas as well.