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Factors affecting concentration of citrate in dialyzers when using citrate hemodialysate in vitro
Author(s) -
Baosong G.,
Ning N.,
Ganglian Y.,
Lin G.,
Liangqi W.,
Ruijun G.
Publication year - 2005
Publication title -
hemodialysis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 47
eISSN - 1542-4758
pISSN - 1492-7535
DOI - 10.1111/j.1492-7535.2005.1121u.x
Subject(s) - hemodialysis , in vitro , fiber , medicine , chromatography , citric acid , biomedical engineering , chemistry , biochemistry , organic chemistry
Objective: To observe the factors that affect the citrate concentration in hollow fiber when using citrate hemodialysate. Methods: By modeling hemodialysis in vitro, we studied 6 types of hemodialyzers at different blood flow rates, different dialysate flow‐rate, and different fluids in vitro to detect the citrate concentration in hollow fiber. Results: The citrate concentrations in different hemodialyzers were F60 > FB‐130UGA > GA‐HP130 > F6 > FB‐130AGA > WS‐70 in turn. The concentrations at different blood flow‐rates were different 100 mL/min > 200 mL/min. Conclusions: The concentration of citrate in hollow fiber is affected by different types of hemodialyzers and different blood as well as dialysate flow‐rates. To achieve anticoagulation when using citrate hemodialysate, we must select suitable hemodialyzer such as FB‐130UGA.