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Experience of application maxipimi at patients with a terminal stage chronic renal insufficiency at allotransplantation of a kidney
Author(s) -
R.Z. Ismagilov,
T.A. Bapiev,
A.K. Zainalov,
T.B. Shynybaev,
T.I. Rahimbekov,
A.N. Syzganov‘s
Publication year - 2005
Publication title -
hemodialysis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 47
eISSN - 1542-4758
pISSN - 1492-7535
DOI - 10.1111/j.1492-7535.2005.1121cj.x
Subject(s) - medicine , sepsis , allotransplantation , surgery , hemodialysis , antibiotics , stage (stratigraphy) , kidney , chronic renal insufficiency , kidney transplantation , antibiotic therapy , transplantation , renal function , paleontology , microbiology and biotechnology , biology
The analysis of infectious complications in patients after allotransplantation of a donor kidney. For the dynamic analysis of frequency of infection‐purulent complications, all patients were divided into 2 groups. The first, control group included 33 patients who were operated from 2000 to 2002 (men‐21, women‐12, adults‐28, children‐5). The second, basic group included 35 patients (men‐22 and women‐13, adult‐28, children‐7), after allotransplantations, which have transferred operation–transplantations of kidney with 2003 on 2004. In the first group purulent–septic complications were marked at 9 patients (27.2%), from them two (6%) have died of a sepsis on a background of antibacterial therapy (cephalosporini 3 generations). Duration of treatment made from 7 up to 15 days. In the second group in the postoperative period purulent – septic complications were marked at 5 of 35 patients (14,2%). All 35 patients in the second group after allotransplantation of a donor kidney carried out preventive antibacterial therapy maxipimi (cephalosporini IV generations) on dosage 1 gram 2 times per day in a combination with amykini intravenously during 7 days. Cases of development of sepsis in this group of patients were not observed. Thus, estimating the received results, it is possible to draw the conclusion, application of antibiotics of a wide spectrum (cephalosporini IV generations) the patient with a terminal stage chronic renal insufficiency after allotransplantation of a donor kidney were lowered with quantity of suppurations of postoperative wounds and occurrence of infectious complications on 13%.