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Periodic stupor‐like states in progressive supranuclear palsy
Author(s) -
SASAYAMA Daimei,
MIYASHITA Mitsuhiro,
FUKUDA Takahiro,
TAKAHASHI Toru,
INUZUKA Shin,
WASHIZUKA Shinsuke,
HANIHARA Tokiji,
AMANO Naoji
Publication year - 2007
Publication title -
psychogeriatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 32
eISSN - 1479-8301
pISSN - 1346-3500
DOI - 10.1111/j.1479-8301.2007.00191.x
Subject(s) - progressive supranuclear palsy , stupor , medicine , atrophy , parkinsonism , corticobasal degeneration , thalamus , gliosis , psychology , neuroscience , pathology , psychiatry , encephalopathy , disease
Four patients with progressive supranuclear palsy presented with various psychiatric symptoms. Periodic stupor‐like states due to fluctuations of consciousness were observed in all four cases. Magnetic resonance imaging showed severe dilatation of the third ventricle suggesting atrophy of the thalami. Neuropathological examination in one of the cases confirmed severe fibrillary gliosis in the intralaminar thalamic nucleus. So far, few studies have focused on periodic stupor‐like states observed in progressive supranuclear palsy patients. From our cases and from the literature, we postulate that the lesions in the intralaminar thalamic nuclei may have close relevance to the stupor‐like states seen in progressive supranuclear palsy patients.