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Pregnancy‐induced Cushing’s syndrome in recurrent pregnancies: Case report and literature review
Author(s) -
ACHONG Naomi,
D’EMDEN Michael,
FAGERMO Narelle,
MORTIMER Robin
Publication year - 2012
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2011.01388.x
Subject(s) - pregnancy , medicine , etiology , obstetrics , cushing syndrome , fetus , pediatrics , endocrinology , genetics , biology
Pregnancy in women with Cushing’s syndrome (CS) is uncommon. It is associated with significant maternal and fetal complications. Pregnancy‐induced Cushing’s syndrome is exceptionally rare with fewer than ten cases reported in the world literature and none in Australia or New Zealand. We describe a woman with possible recurrent pregnancy‐induced CS complicating five pregnancies over a 7‐year period. We discuss the changes in the hypothalamic–pituitary–adrenal axis during normal pregnancy together with the diagnosis, aetiology and management of CS in pregnancy.