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Diet and IVF pilot study: Short‐term weight loss improves pregnancy rates in overweight/obese women undertaking IVF
Author(s) -
MORAN Lisa,
TSAGARELI Victoria,
NORMAN Robert,
NOAKES Manny
Publication year - 2011
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2011.01343.x
Subject(s) - overweight , medicine , waist , weight loss , pregnancy , obesity , obstetrics , fertility , gynecology , embryo transfer , pregnancy rate , in vitro fertilisation , population , biology , environmental health , genetics
Obesity worsens and modest weight loss improves female fertility. Overweight women were randomised to lifestyle or standard treatment pre‐ in vitro fertilisation with treatment cessation at embryo transfer. There was a greater reduction in weight ( P < 0.001) for lifestyle treatment (−3.8 ± 3.0 kg, P < 0.001) compared with no changes for standard treatment (−0.5 ± 1.2 kg, P = 0.092). Both the intervention (−5.3 ± 4.6 cm) and control (−3.5 ± 3.5 cm) group had reductions in waist circumference ( P < 0.001) with no differences between the two groups ( P = 0.215). The overall pregnancy rate was 53% (20/38) for the intervention and control group combined.