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Human papillomavirus infection: An old disease, a new vaccine
Author(s) -
GILES Michelle,
GARLAND Suzanne
Publication year - 2006
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2006.00580.x
Subject(s) - medicine , cervical cancer , hpv vaccines , human papillomavirus , disease , hpv infection , vaccination , clinical trial , immunology , public health , intensive care medicine , virology , cancer , pathology
Human papillomavirus (HPV) infection is common and causes a wide spectrum of disease. With recent advances in the development of prophylactic HPV vaccines, it is likely that these will be licensed for use in the near future. This review focuses on the science behind HPV vaccines, published clinical trial results for both prophylactic and therapeutic HPV vaccines, important issues relevant to implementation and cost‐effectiveness models of HPV vaccination programs. It may be that an HPV vaccine that protects against the complications of HPV infection such as cervical cancer will be one of the most significant public health initiatives of this decade.