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Preliminary report: correct diagnosis of sex in fetal cells isolated from cervical mucus during early pregnancy
Author(s) -
MANTZARIS Debbie,
CRAM David,
HEALY Christine,
HOWLETT Donna,
KOVACS Gab
Publication year - 2005
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2005.00492.x
Subject(s) - cervical mucus , mucus , pregnancy , obstetrics , fetus , early pregnancy factor , medicine , andrology , gynecology , biology , gestation , ecology , genetics , ovulation
The aim of this study was to determine the accuracy of sexing fetal cells isolated from cervical mucus. Immunopositive cells identified using a fetal‐specific antibody were isolated and subjected to genetic analysis. Fetal sex was predicted in all 22 samples, as confirmed by analysis of the corresponding placental tissue. This study validates the accuracy of our test for sex diagnosis and confirms the ability to effectively recover and analyse fetal cells from the cervical mucus during early pregnancy.