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Colposcopic and histologic findings in women with a cytologic diagnosis of atypical squamous cells of undetermined significance
Author(s) -
YARANDI Fariba,
IZADI MOOD Narges,
MIRASHRAFI Fatemeh,
EFTEKHAR Zahra
Publication year - 2004
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.2004.00299.x
Subject(s) - ascus (bryozoa) , colposcopy , squamous intraepithelial lesion , medicine , gynecology , cervix , cytology , biopsy , population , cervical intraepithelial neoplasia , not otherwise specified , cervical cancer , cancer , pathology , botany , ascospore , spore , environmental health , biology
Background: The optimal method for managing a patient diagnosed with atypical squamous cells of undetermined significance (ASCUS) has not yet been established. The interim guidelines published by the National Cancer Institute suggest that a patient should be referred for colposcopy after the second ASCUS diagnosis within 2 years. Aim: To assess the significance of ASCUS in predicting the presence of underlying squamous intraepithelial lesion (SIL) of the uterine cervix. Study population: Women undergoing colposcopy for ASCUS cytology at a teaching hospital in Tehran University, in the years 1998–2001, considered eligible to enter this retrospective study. Results: Of the 266 patients who underwent colposcopy, 28 (11%) had low‐grade squamous intraepithelial lesion (LSIL), 16 (6.3%) had high‐grade squamous intraepithelial lesion (HSIL) two (0.8%) had squamous cell carcinoma (SCC), and 48 (18.8%) had flat condyloma. Conclusion: Atypical squamous cells of undetermined significance (ASCUS) on a cervical smear is a good marker for detecting underlying SIL and condyloma. Thus, immediate colposcopy and directed biopsy are appropriate follow‐up procedures.