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Study of Cervicovaginal Fetal Fibronectin Status to Guide Treatment of Threatened Preterm Labour
Author(s) -
Watson David L.,
Kim Stephano J.,
Humphrey Michael D.
Publication year - 1998
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1998.tb02998.x
Subject(s) - fetal fibronectin , medicine , tocolytic , fibronectin , preterm labour , obstetrics , fetus , tocolytic agent , preterm labor , gynecology , pregnancy , gestation , biology , cell , genetics
Summary: A sequential controlled pilot study of 48 women (16 study, 32 controls) was performed to explore the place of bedside fetal fibronectin testing in the managment of apparent preterm labour; 80% of the study group were successfully managed without tocolytic therapy, on the basis of fetal fibronectin test results, without detriment to the babies. Rapid bedside fetal fibronectin testing holds promise that protocols for management of women in apparent preterm labour, with intact membranes and without significant cervical dilatation, may be altered so that most of the unnecessary use of tocolytic drugs is avoided.