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Predominance of a Maternal History of Diabetes for Patients with Non‐insulin‐independent Diabetes Mellitus. Implications for the Intrauterine Transmission of Diabetes
Author(s) -
Mosesl R.,
Rodda M.,
Griffiths R.
Publication year - 1997
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1997.tb02408.x
Subject(s) - diabetes mellitus , gestational diabetes , medicine , family history , population , insulin , endocrinology , pregnancy , obstetrics , gestation , biology , environmental health , genetics
Summary: In Europid populations, patients with non‐insulin‐dependent diabetes mellitus (NIDDM) are more than twice as likely to have a mother than a father with diabetes. We have examined this aspect in an Australian population. For this purpose records of 1,000 consecutive patients with NIDDM were reviewed. A history of diabetes was present in 193 mothers (19.3%) and in only 86 fathers (8.6%) (p<0.0001). The predominance of a maternal history of diabetes in patients with NIDDM is suggestive of a maternal transmission of this disorder. This metabolic tendency may develop due to an adverse intrauterine environment in women with undiagnosed gestational diabetes mellitus.