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Survival and Neonatal and Neurodevelopmental Outcome of 24–29 Week Gestation Infants According to Primary Cause of Preterm Delivery
Author(s) -
Gray Peter H.,
Hurley Thomas M.,
Rogers Yvonne M.,
O'Callaghan Michael J.,
Tudehope David I.,
Burns Yvonne R.,
Phty M.,
Mohay Heather A.
Publication year - 1997
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1997.tb02245.x
Subject(s) - medicine , chorioamnionitis , cerebral palsy , gestation , obstetrics , necrotizing enterocolitis , pediatrics , preeclampsia , preterm delivery , pregnancy , complication , surgery , genetics , psychiatry , biology
Summary: A total of 189 infants of 24–29 weeks' gestation were born in a regional perinatal centre during a 2‐year period. They were divided into groups according to the primary cause of preterm delivery: antepartum haemorrhage (n=37, 20%), preeclampsia (n=27, 14%), preterm premature rupture of membranes (n=64, 34%), preterm labour (n=27, 14%), chorioamnionitis (n=16, 8%), other complications (n=18, 10%). The perinatal mortality rate (PMR) was 286/1,000 of whom 44% were stillbirths. The ‘other complication’ group had the highest PMR due to a large number of intrauterine deaths, with no differences in neonatal mortality between the groups. Preeclampsia was associated with an increased risk of necrotizing enterocolitis and chorioamnionitis was associated with an increased risk of periventricular haemorrhage. Follow‐up to at least 2 years was performed in 122 (97%) of survivors. Cerebral palsy occurred in 7%, while 18% had neurodevelopmental disability. No relationship was found between primary cause of preterm delivery and outcome. This information should be of value in counselling parents when preterm delivery is imminent.