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Antenatal Human Parvovirus B19 Infection and Nonimmune Hydrops Fetalis Presenting as Severe Preeclampsia
Author(s) -
Choong Shawn,
Meagher Simon
Publication year - 1996
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1996.tb02729.x
Subject(s) - hydrops fetalis , preeclampsia , medicine , obstetrics , fetus , parvovirus , pregnancy , in utero , immunology , virus , biology , genetics
EDITORIAL COMMENT: We accepted this paper for publication since the authors believe it is the first report of hydrops fetalis due to parvovirus infection apparently causing severe preeclampsia. This is similar to the ‘maternal preeclampsia syndrome’ classically described with fetal and placental hydrops due to maternal rhesus isoimmunization (A), and which also can occur with fetal and placental hydrops due to fetal alpha thalassaemia major. The authors indicate that treatment of fetal anaemia could possibly result in resolution of the signs of preeclampsia in such cases. Indeed the members of the editorial subcommittee have already heard, on the Australian academic grapevine, of surviving infants treated in utero for anaemia caused by parvovirus and erythroblastosis due to maternal rheus isoimmunization respectively, in 2 mothers with signs of severe preeclampsia. (A) Scott JS. Pregnancy toxaemia associated with Hydrops foetalis, Hydatidiform mole and Hydramnios. J Obstet Gynaecol Br Emp 1958; 65:689–701. William Blair‐Bell Memorial Lecture delivered at the Royal College of Obstetricians and Gynaecologists on May 30, 1958.