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Randomized Prospective Intervention Study of Human Cervical Wart Virus Infection
Author(s) -
Ward Bruce G.,
Thomas Ifor L.
Publication year - 1994
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1994.tb02686.x
Subject(s) - medicine , randomized controlled trial , ablative case , dysplasia , human papillomavirus , surgery , hpv infection , gynecology , cervical cancer , radiation therapy , cancer
Summary: Between February, 1988, and January, 1991,222 women with histologically proven cervical wart virus infection without dysplasia were randomized to be managed by 1 of 4 protocols. Group 1 acted as control, Group 2 were asked to use condoms for 6 months, Group 3 underwent local ablative therapy and Group 4 were asked to use condoms after ablative therapy. Assessment at 2 and 3 years of follow‐up showed no statistically significant superiority for treatment over observation. Defaulters from follow‐up were over 50% by the completion of the study.