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Cervical Ripening Induces Labour Through Interleukin 1β
Author(s) -
George Susan Shanthi,
Matthews Jiji,
Jeyaseelan L.,
Seshadri Lakshmi
Publication year - 1993
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1993.tb02088.x
Subject(s) - ripening , foley catheter , foley , medicine , cervix , labor induction , interleukin 6 , obstetrics , gynecology , catheter , biology , oxytocin , surgery , cytokine , food science , cancer
Summary: In order to study the Interleukin 1β (IL‐1β) levels in mechanical cervical ripening with Foley catheter, IL‐1β levels in amniotic fluid of 12 women before and after cervical ripening were compared with those in 23 women in spontaneous active labour. IL‐1β was present in 81.8% of patients after cervical ripening and in none prior to it. In women with spontaneous labour 69.6% had immunodetectable IL‐1β. Women with spontaneous labour and those sampled after cervical ripening had similar IL‐1β levels in the amniotic fluid. Cervical ripening with Foley catheter is associated with high levels of IL‐1β and this probably induces labour.