Premium
Conception in the Resistant Ovary Syndrome Occurring during Hormone Replacement Therapy: A Report of 2 Cases
Author(s) -
Jequier Anne M.
Publication year - 1990
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1990.tb03257.x
Subject(s) - norethisterone , medicine , mestranol , pill , ovary , norethisterone acetate , ovulation , hormone , hormone replacement therapy (female to male) , estrogen , gynecology , physiology , endocrinology , pharmacology , population , family planning , research methodology , environmental health , testosterone (patch)
EDITORIAL COMMENT: We accepted this paper for publication as it provides readers with a useful account of the resistant ovary syndrome and information comparing the doses of hormones in the oral contraceptive pill and hormone replacement therapy. ABSTRACT Two patients with resistant ovary syndrome are described. Both patients conceived while on hormone replacement therapy. Both women were taking the phasic preparation containing mestranol and norethisterone known as ‘Menophase’ (Syntex Pharmaceuticals Ltd). The possible mechanism of action of this type of hormone preparation in the induction of ovulation in patients with resistant ovary syndrome is discussed.