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Primary Amenorrhoea in a Triple X Female
Author(s) -
Itu Mohapatra,
Neelam Taneja,
Ammini A.C.,
Kucheria K.
Publication year - 1990
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1990.tb02039.x
Subject(s) - incidence (geometry) , primary amenorrhea , trisomy , premature ovarian failure , population , gynecology , medicine , gonadal dysgenesis , amenorrhea , secondary sex characteristic , obstetrics , pediatrics , hormone , endocrinology , biology , pregnancy , genetics , physics , environmental health , optics
Summary: The incidence of trisomy X in the newborn population is estimated to be 1 in 1,000 liveborn females. Most of them have normal physical appearance and puberty. Therefore, the reported number of triple X females in the literature is low. We herein report one patient with triple X chromosomes, primary amenorrhoea and normal intelligence. Steroid hormonal levels, clinical and ultrasound findings were suggestive of ovarian failure/gonadal dysgenesis. This case emphasizes the need for chromosomal analysis in women presenting with premature ovarian failure leading to primary or secondary amenorrhoea.