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Risk Factors for Neonatal Infection
Author(s) -
Spaans Willem A.,
Knox Andrew J.,
Koya Hanifa B.,
Mantell Colin D.
Publication year - 1990
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1990.tb02021.x
Subject(s) - medicine , incidence (geometry) , pneumonia , sepsis , odds ratio , logistic regression , risk factor , neonatal sepsis , birth weight , pediatrics , low birth weight , univariate analysis , neonatal infection , retrospective cohort study , pregnancy , multivariate analysis , physics , biology , optics , genetics
Summary: A retrospective case‐control study was designed to assess risk factors for neonatal infection. Nonprivate patients (8,215) who delivered in a period from January 1, 1983 to June 30, 1988 were studied. Ninety three cases of conjunctivitis (incidence 2.4/1,000), 104 cases of pneumonia (incidence 2.8/1,000), and 50 cases of sepsis (incidence 1.3/1,000) were identified. Group B streptococcus was cultured from septic neonates in 46%. Calculated Odds ratio's indicated prematurity/low birth‐weight (OR 6.9) and antepartum fetal tachycardia (OR 6.3) as important risk factors for pneumonia/ sepsis. Prematurity/low birth‐weight (OR 3.0) and an abnormal presentation in the birth canal (OR 2.8) were identified as risk factors for conjunctivitis. After testing all the risk factors found by univariate analysis in a logistic regression model tachycardia (chi 2 35.21, p< 0.001) remained an independent predictor for neonatal pneumonia/ sepsis and abnormal vaginal presentation (chi 2 7.58, p 0.006) for conjunctivitis.