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Which is the Best Test to Detect the Polycystic Ovary?
Author(s) -
Eden John A.
Publication year - 1988
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1988.tb01668.x
Subject(s) - polycystic ovary , free androgen index , luteinizing hormone , sex hormone binding globulin , testosterone (patch) , ovary , endocrinology , medicine , androgen , biology , gynecology , hormone , andrology , obesity , insulin resistance
Summary: Laparoscopy was used to characterize the ovaries of a group of infertile women. Patients with polycystic ovaries (PCO) were compared with those with normal ovaries. A free androgen index (FAI) >4.5 was 100% specific and sensitive for detecting the PCO in a group of women with oligomenorrhoea. Overall, a biochemical ‘screen’ consisting of a luteinizing hormone (LH) level > 10 U/1, testosterone (T) >2.6nmol?/l, sex hormone binding globulin (SHBG) <31nmol/l or a FAI >4.5 was 89% sensitive and 98% specific for PCO, which is comparable with the reliability of ultrasound for detecting the PCO.