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Atypical Condylomas of the Cervix Uteri in Singapore Women: A Histopathological and Immunohistochemical Stud
Author(s) -
Sutherland I. H.,
Arulkumaran S.,
Kitchener H. C.
Publication year - 1986
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1986.tb01554.x
Subject(s) - koilocyte , colposcopy , cervix , cervical intraepithelial neoplasia , atypia , pathology , immunohistochemistry , subclinical infection , intraepithelial neoplasia , hpv infection , medicine , carcinogenesis , atypical hyperplasia , cervical cancer , cancer , prostate
Summary: Subclinical flat cervical warts are commonly recognized by means of colposcopy. These warty lesions frequently contain cellular atypia of a varying degree showing all the features of cervical intraepithelial neoplasia (CIN) together with the features of wart virus infection e.g. koilocytosis. Human papillomavirus (HPV) antigens and DNA have been found in these lesions which can be called atypical condylomas. The presence of such markers in lesions regarded as having neoplastic potential implicates HPV in cervical carcinogenesis.