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Hydatidiform Mole In Victoria: Aetiology and Natural History
Author(s) -
Olesnicky G.,
Long A. R.,
Quinn M. A.,
Pepperell R. J.,
Fortune D. W.,
Kneale B. L. G.
Publication year - 1985
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1985.tb00593.x
Subject(s) - molar pregnancy , etiology , choriocarcinoma , mole , medicine , gynecology , incidence (geometry) , obstetrics , artificial insemination , gestation , pregnancy , retrospective cohort study , partial hydatidiform mole , surgery , fetus , biology , genetics , physics , placenta , optics
Summary: A retrospective study was made of 455 patients referred to the Hydatidiform Mole Register of the Royal Women's Hospital from 1973 — 1982 who fulfilled the criteria for diagnosis of hydatidiform mole. The incidence of hydatidiform mole was 1:1,357 livebirths in Victoria. Age greater than 40 years (P < 0.001), nulliparity (P < 0.005) and parity greater than 4 (P < 0.001) were the only predisposing factors found. An association with artificial insemination with donor semen was also noted (P < 0.025). The need for further treatment for persistent trophoblastic activity (13.6% of patients) was independent of the method of evacuation employed and of gestation at evacuation. Only 2 cases of histologically proven postmolar choriocarcinoma occurred, one of which was also the only death recorded from all patients registered following a molar pregnancy.