Premium
α Thalassaemia in Pregnancy
Author(s) -
Trent R. J.,
Yakas J.,
Black J.,
Kronenberg H.
Publication year - 1984
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1984.tb03319.x
Subject(s) - pregnancy , genotype , medicine , genetic counseling , prenatal diagnosis , fetus , obstetrics , pediatrics , gene , genetics , biology
Summary: α thalassaemia as a cause of hypochromic, microcytic anaemia in pregnancy is described. The problems associated with accurate diagnosis of this condition and prediction of fetal outcome is now made much easier by use of recombinant DNA techniques such as gene mapping. Two Greek Cypriot families with α thalassaemia have been studied by DNA mapping. Definitive assessment of α thalassaemia genotype in these cases enabled confident genetic counselling.