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Improved Glucose Tolerance in Gestational Diabetic Women on a Low Fat, High Unrefined Carbohydrate Diet
Author(s) -
Sc Christopher J. Nolan B Med
Publication year - 1984
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1984.tb01483.x
Subject(s) - postprandial , medicine , endocrinology , carbohydrate , gestational diabetes , triglyceride , chemistry , diabetes mellitus , gestation , biology , cholesterol , pregnancy , genetics
Summary: In a randomized cross‐over study 5 gestational diabetic women were tested on a low fat, high unrefined carbohydrate (HC) diet and a low carbohydrate (LC) diet for a period of 4 days each. Glucose tolerance was shown to be significantly improved on the HC diet compared to the LC diet (p <0.05). Urinary glucose output was 50% lower on the HC diet (1.3 ±pM 1.1 mmol/d) than on the LC diet (2.6 ±pM 3.0 mmol/d), although this difference was not statistically significant. Fasting free fatty acid levels were significantly lower on the HC diet (HC 590 ±pM 270 μmol/1, LC 690 ±pM 270 μmol/1; p <0.02); as were the fasting cholestrol levels (HC 5.9 ±pM 1.1 mmol/1, LC 6.3 ±pM 1.1 mmoi/I; p <0.01). Fasting plasma glucose, 2 h postprandial plasma glucose, and fasting plasma triglyceride levels did not differ on the 2 diets. These pilot study results suggest that diets low in fat and high in unrefined carbohydrate content are beneficial to the management of women with gestational diabetes.