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The Effect Of Ampicillin and Colistin On Post‐Caesarean Section Endometritis With Identification Of Possible Risk Factors
Author(s) -
Birkenfeld Arie,
Anteby Shaoul O.
Publication year - 1983
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1983.tb00579.x
Subject(s) - endometritis , medicine , caesarean section , colistin , ampicillin , premature rupture of membranes , antibiotics , risk factor , obstetrics , pregnancy , surgery , fetus , biology , genetics , microbiology and biotechnology
Summary Two hundred and seventy eight women undergoing Caesarean section were evaluated retrospectively to determine the value of prophylactic antibiotic treatment. The patients were divided into 2 groups: 180 women who received no prophylactic treatment and 98 who were treated prophylactically with ampicillin and colistin (Colymycin). Significantly lower rates of infection with prophylactic treatment were found in all groups studied (P < 0.001) (P < 0.05 in the group with premature rupture of membranes). Premature rupture of membranes was found to be the only risk factor significantly altering the rate of infection in the untreated group. Patients with premature rupture of membranes or with prolonged stay in the labour room prior to surgery had a significantly higher rate of infection even after the introduction of prophylactic treatment with ampicillin and colistin (P < 0.001).