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Is Diagnostic Gonadotrophs Stimulation Useful?
Author(s) -
Wu Roxanne L.,
Shearman Rodney P.,
Fraser Ian S.
Publication year - 1980
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1980.tb00895.x
Subject(s) - polycystic ovarian disease , stimulation , medicine , polycystic ovary , gonadotropin , differential diagnosis , diagnostic test , gynecology , urology , endocrinology , pathology , hormone , pediatrics , diabetes mellitus , insulin resistance
Summary: Urinary excretion of oestrogens in response to stimulation with a standardized dose of gonadotrophin has been used previously in the differential diagnosis of oligomenorrhoea/amenorrhoea. Patients with polycystic ovarian disease were said to have a characteristic excessive response. In the present study, some patients with laparoscopically proven polycystic ovaries did not show such an excessive response, while others with laparoscopically normal ovaries did. A high LH/FSH ratio correlated well with the laparoscopic finding of polycystic ovaries. It is concluded that where there are adequate facilities for diagnostic laparoscopy and determination of plasma gonadotrophins, there is no further place for the routine use of the standardized gonadotrophin stimulation test in the evaluation of suspected polycystic ovarian disease.