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A Patient with Pure Gonadal Dysgenesis, Gonadal Tumour and Virilisation
Author(s) -
Schokman F. C. M.,
Correy J. F.
Publication year - 1979
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1979.tb01384.x
Subject(s) - gonad , uterus , gonadal dysgenesis , biology , karyotype , ovary , malignancy , gynecology , medicine , endocrinology , genetics , chromosome , gene
Summary: A phenotypic female, karyotype XY, presented with virilisation and amenorrhoea. The gonads showed evidence of oestrogen and testosterone production and, in view of the risk of malignancy, a laparotomy was performed. A streak gonad was present on one side with a streak gonad containing discrete tumours on the other. The uterus and Fallopian tubes were present. Removal of the gonads and uterus and subsequent oestrogen replacement therapy have produced a satisfactory clinical result.